Chemical Resistance - GE AKTA ready Operating Instructions Manual

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14.3 Chemical resistance

External surfaces, cabinet
Wetted parts
You must consider the compatibility of the wetted parts and your process chemicals so
that no negative interaction takes place. Also ensure that your process chemicals do
not damage the system components, compromising the safety of the system.
Contact your local GE Healthcare representative if you are not sure of the compatibility
of your chemicals.
ÄKTA ready flow paths are resistant to chemical agents used in protein recovery, including
buffer solutions for adsorption, elution and washing, and to solutions effective in cleaning
and storage. The following table lists chemicals that may be used with ÄKTA ready. The
concentrations listed are not normally exceeded during an operating cycle.
The information in the table below is valid for a maximum exposure time of 48 hours.
Note:
List of chemicals allowed
Note:
Chemical allowed
Acetic acid
Acetone
Aqueous buffers pH 2-12
Arginine
Ammonium sulfate
Benzyl alcohol
DTE/DTT
ÄKTA ready Operating Instructions 28960345 AD
Water with weak detergent should be used for daily cleaning of the cabinet.
70% ethanol or 2-propanol (Isopropanol) can be used for sanitization.
The table should be used only as a guide. The effects of a chemical will gener-
ally be more severe at higher temperatures.
Note that the combined effects of agents have not been taken into account.
The percentage in the table is given in %(v/v).
14 Reference information

14.3 Chemical resistance

Concentration
1 M
2.5%
<0.3 M
2 M
4 M
2%
100 mM
207

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